Many gangue minerals can host native gold and was noted that the gold does not replace the host mineral. Apparently, gold is readily liberated by comminution operations and then can be recovered by gravimetry, flotation and cyanidation. The process is influenced by the particle size due to the efficiency of the processes mentioned are influenced by the gold particle size. If there is particular mineral association, it wil be advantageous to recover that specific mineral. The type of gangue, for example quartz, silicates, carbonates and iron oxides have an effect on the recovery process due to modify the slurry properties. A particular case can be considered when the amount of clay minerals is high. Normally, the latter is a critical case.